| Alternative Name: | Interleukin-22, IL-TIF, IL-10-related T-cell-derived-inducible factor, Cytokine Zcyto18 |
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| MW: | Dimer, ~16.9/33.8 kDa |
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| Source: | Produced in E. coli. Contains 147/294 amino acids. |
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| UniProt ID: | Q9GZX6 |
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| Formulation: | Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium citrate, pH 3.0. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Endotoxin Content: | ≤1 EU/µg protein (LAL test) |
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| Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains. IL-22 is a potent mediator of cellular inflammatory responses. |
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| Regulatory Status: | RUO - Research Use Only |
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