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IL-19 (mouse), (recombinant)

 
ENZ-PRT246-0010 10 µg 260.00 USD
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Product Specification

Alternative Name:Interleukin-19
 
MW:~17.7 kDa
 
Source:Produced in E. coli. Contains 153 amino acids.
 
UniProt ID:Q8CJ70
 
Formulation:Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg protein (LAL test)
 
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Interleukin-19 (IL-19) is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex to activate STAT3 signaling. IL-19 induces IL-6 and tumor necrosis factor alpha (TNF-α) expression in monocytes, and promotes T helper 2 cell-mediated immune responses. IL-19 production is up-regulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.
 

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