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IL-11 (human), (recombinant)

 
ENZ-PRT242-0010 10 µg 260.00 USD
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Product Specification

Alternative Name:Interleukin-11, AGIF, Adipogenesis Inhibitory Factor, Oprelvekin
 
MW:~19.3 kDa
 
Source:Produced in E. coli. Contains 179 amino acids.
 
UniProt ID:P20809
 
Formulation:Lyophilized from a sterile (0.2 micron) filtered solution containing 0.1% Trifluoroacetic Acid (TFA).
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg protein (LAL test)
 
Biological Activity:TF-1 cell proliferation; ≤ 10 ng/mL (≥ 1.0 x 105 units/mg).
 
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover.
 

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