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Growth and Differentiation factor-11 (human), (recombinant)

 
ENZ-PRT236-0020 20 µg 260.00 USD
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Product Specification

Alternative Name:GDF-11, Bone morphogenetic protein 11, BMP-11
 
MW:Dimer, ~12.5/24.9 kDa
 
Source:Produced in E. coli. Contains 109/218 amino acids.
 
UniProt ID:O95390
 
Formulation:Lyophilized from a sterile (0.2 micron) filtered solution containing 0.1% Trifluoroacetic Acid (TFA).
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg protein (LAL test)
 
Biological Activity:Alkaline phosphatase activity in ATDC5 cells; ED50 ≤ 100 ng/mL (≥ 1.0 x 104 units/mg).
 
Reconstitution:Reconstitute in sterile 10mM HCl at 0.1 mg/mL.
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Growth differentiation factor 11 (GDF-11), is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the transforming growth factor-beta receptors ALK4, ALK5, and ALK7 to activate SMAD signaling.
 

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