Alternative Name: | Fibroblast growth factor 1, FGF-1, HBGF-1, β-endothelial growth factor, ECCF-β |
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MW: | ~16.0 kDa |
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Source: | Produced in E. coli. Contains 141 amino acids. |
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UniProt ID: | P05230 |
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Formulation: | Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate, 150 mM sodium sulfate, pH 7.5. |
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Purity: | ≥95% (SDS-PAGE) |
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Endotoxin Content: | ≤1 EU/µg protein (LAL test) |
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Biological Activity: | 3T3 proliferation; ED50 ≤ 2 ng/mL (≥ 5.0 x 105 units/mg). |
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Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -80°C |
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Handling: | Avoid freeze/thaw cycles. |
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Scientific Background: | Acidic fibroblast growth factor (FGF-acidic), is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling. |
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Regulatory Status: | RUO - Research Use Only |
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