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FGF-6 (human), (recombinant)

ENZ-PRT232-0025 25 µg 268.00 USD
ENZ-PRT232-0100 100 µg 940.00 USD
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Product Specification

Alternative Name:Fibroblast growth factor 6, Heparin secretory-transforming protein 2, HST-2, HSTF-2, HBGF-6
MW:~18.9 kDa
Source:Produced in E. coli. Contains 169 amino acids.
UniProt ID:P10767
Formulation:Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5.
Purity:≥95% (SDS-PAGE)
Endotoxin Content:≤1 EU/µg protein (LAL test)
Biological Activity:3T3 proliferation with 1 µg heparin; ED50 ≤ 1 ng/mL (≥ 1.0 x 105 units/mg).
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
Long Term Storage:-80°C
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
Scientific Background:Fibroblast growth factor 6 (FGF-6) is an important factor driving muscle differentiation and regeneration. FGF-6 is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts.

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