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Activin-A (mouse), (recombinant)

 
ENZ-PRT225-0100 100 µg 762.00 USD
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Product Specification

Alternative Name:Inhibin β-1, FRP, FSH-releasing protein
 
MW:~26.2kDa
 
Source:Produced in E. coli. Non-glycosylated homodimer, containing two 117 amino acid chains.
 
UniProt ID:Q04998
 
Formulation:Lyophilized from a sterile filtered solution containing 0.1% TFA.
 
Purity:≥95% (HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm)
 
Endotoxin Content:≤0.05 EU/μg protein measured by kinetic LAL analysis.
 
Biological Activity:The activity is determined by the ability to induce cytotoxicity of MPC-11 cells which is typically observed at concentations <2ng/ml.
 
Reconstitution:Reconstitute in sterile water at 0.1mg/mL
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Activin A is a member of the TGF-β family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N-terminal propeptide is cleaved from each.
 

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