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WISP-2 (human), (recombinant)

 
ENZ-PRT222-0020 20 µg 410.00 USD
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Product Specification

Alternative Name:CTGF-L, CCN5, Connective tissue growth factor-like protein, WNT1-inducible-signaling pathway protein 2
 
MW:~24.4 kDa
 
Source:Produced in E. coli. Contains 228 amino acids.
 
UniProt ID:O76076
 
Formulation:Lyophilized. Contains 0.1% trifluoroacetic acid.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg (LAL test)
 
Reconstitution:Reconstitute in sterile 10 mM acetic acid at 0.1 mg/mL.
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:WNT1-inducible-signaling pathway protein 2 (WISP-2) is a member of the CYR61/CTGF/NOV (CCN) family of regulatory factors. WISP-2 is expressed in ectodermal, mesodermal, and endodermal lineages, including primary osteoblasts, fibroblasts, mesenchymal stem cells, and adipogenic precursor cells. WISP-2 is a canonical WNT ligand that regulates cell proliferation, adhesion, and metastasis. Secreted WISP-2 promotes mesenchymal precursor cell proliferation and maintains them in an undifferentiated state. WISP-2 promotes osteoblast adhesion and inhibits osteocalcin production in bone-forming osteoblasts.
 

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