| Alternative Name: | KGF, Keratinocyte growth factor, Fibroblast growth factor 7 |
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| MW: | 17-30kDa |
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| Source: | Produced in HEK cells. Glycosylated protein. |
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| UniProt ID: | P21781 |
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| Formulation: | Lyophilized from 1 mg/mL in 1X PBS. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Appearance: | White powder. |
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| Reconstitution: | Reconstitute in sterile water to not less than 100 µg/mL |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Use/Stability: | The reconstituted solution can be stored at +4°C for 1 week. |
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| Handling: | After reconstitution, prepare aliquots and store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% BSA or serum). |
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| Scientific Background: | FGF7 is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities. FGF7 is involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. |
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| Regulatory Status: | RUO - Research Use Only |
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