| Alternative Name: | CCL21, 6Ckine |
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| Sequence: | SDGGAQD CCLKYSQRKI PAKVVRSYRK QEPSLGCSIP AILFLPRKRS QAELCADPKE LWVQQLMQHL DKTPSPQKPA QGCRKDRGAS KTGKKGKGSK GCKRTERSQT PKG |
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| MW: | Monomer, 12.3 kDa (111 amino acids) |
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| Source: | Produced in E. coli. |
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| UniProt ID: | O00585 |
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| Formulation: | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% trifluoroacetic acid (TFA). |
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| Purity: | ≥95% (SDS-PAGE) |
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| Endotoxin Content: | ≤1 EU/µg (LAL) |
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| Reconstitution: | Reconstitute with sterile water at 0.1 mg/mL. |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -80°C |
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| Use/Stability: | Reconstituted solution is stable for 3 months when stored at -20°C to -80°C and for 1 month when stored at 4°C after reconstituting as directed. |
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| Handling: | Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution and allow several minutes for complete reconstitution. Do not vortex. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C. Avoid freeze/thaw cycles. |
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| Scientific Background: | Exodus-2 (CCL21 or 6Ckine), is a chemokine produced in the lymph nodes and spleen. Exodus-2 signals through the chemokine receptor CCR7 to regulate thymocyte and activated T cell migration and also mediates the homing of lymphocytes to the lymphatic system. Human and mouse Exodus-2 share > 85% amino acid identity. |
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| Regulatory Status: | RUO - Research Use Only |
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