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IL-1α (human), (recombinant)

 
ENZ-PRT186-0010 10 µg 202.00 USD
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Product Specification

Alternative Name:Interleukin-1α, Hematopoietin-1, Lymphocyte-activating factor , LAF, Endogenous pyrogen, Leukocyte endogenous mediator, LEM, Mononuclear cell factor, MCF, IL-1F1
 
MW:~18.0 kDa
 
Source:Produced in E. coli.
 
UniProt ID:P01583
 
Formulation:Lyophilized from 10mM TRIS, pH 8.0, containing 50mM NaCl.
 
Purity:≥98% (SDS & HPLC)
 
Purity Detail:Sterile filtered through a 0.2 micron filter.
 
Biological Activity:Stimulates the proliferation of mouse D10S cells.
 
Specific Activity:1x109 units/mg. Determined by the ability of IL-1α to stimulate the proliferation of mouse D10S cells. The expected ED50 is typically ≤0.001 ng/mL.
 
Reconstitution:Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-20°C
 
Handling:Centrifuge vial before opening. Do not vortex. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -20°C to -80°C. Avoid freeze/thaw cycles.
 
Scientific Background:Interleukin-1α (IL-1α) is a protein of the interleukin-1 family. In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes and treat diseases.
 

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