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IL-13 (human), (recombinant)

 
ENZ-PRT183-0010 10 µg 212.00 USD
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Product Specification

Alternative Name:Interleukin-13, NC30
 
MW:~12.6 kDa
 
Source:Produced in E. coli.
 
UniProt ID:P35225
 
Formulation:Lyophilized from 20mM sodium phosphate, pH 7.0.
 
Purity:≥98% (SDS & HPLC)
 
Purity Detail:Sterile filtered through a 0.2 micron filter.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-20°C
 
Scientific Background:IL-13 (interleukin-13) is primarily produced by activated T cells and has many of the same biological properties as IL-4. IL-13 suppresses the expression of pro-inflammatory cytokines such as IL-1, IL-6, TNF-α and IL-8 by monocytes/macrophages, induces CD23 expression on B cells, promotes B cell proliferation, stimulates secretion of IgE and IgG4, and induces IFN-γ production by NK cells. IL-13 has been shown to inhibit the replication of HIV both in vitro and in vivo. IL-13 induces many phenotypes of allergic lung diseases, including airway hyper responsiveness, goblet cell metaplasia and mucus hypersecretion that contribute to airway obstruction.
 

Product Literature References

Pro-Inflammatory Activation of A New Immortalized Human Microglia Cell Line: M. Chiavari, et al.; Brain Sci. 9, 111 (2019), Abstract;

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