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Growth and differentiation factor-3 (human), (recombinant)

 
ENZ-PRT176-0020 20 µg 202.00 USD
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Product Specification

Alternative Name:GDF-3
 
MW:~26.0 kDa
 
Source:Produced in E. coli.
 
UniProt ID:Q9NR23
 
Formulation:Lyophilized with no additives.
 
Purity:≥98% (SDS & HPLC)
 
Purity Detail:Sterile filtered through a 0.2 micron filter.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-20°C
 
Scientific Background:GDF-3 is a bi-functional protein that has some intrinsic activity and also modulate other TGF-β superfamily members (e.g. potentiates the activity of NODAL). It may also inhibit other TGF-β superfamily members (i.e. BMPs), thus regulating the balance between different modes of TGF-β signaling. It has been shown to negatively and positively control differentiation of embryonic stem cells in mice and humans. This molecule plays a role in mesoderm and definitive endoderm formation during the pre-gastrulation stages of development.
 

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