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MIA (human), (recombinant)

 
ENZ-PRT142-0020 20 µg 202.00 USD
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Product Specification

Alternative Name:Melanoma-derived growth regulatory protein, Melanoma inhibitory activity protein
 
MW:~12.2 kDa
 
Source:Produced in E.coli.
 
UniProt ID:Q16674
 
Formulation:Lyophilized from 15mM sodium phosphate, pH 7.2, containing 75mM NaCl.
 
Purity:≥98% (SDS-PAGE gel & HPLC)
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-20°C
 
Scientific Background:MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.
 

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