| ENZ-KIT179-0200 | 200 tests | 5,159.00 USD |  |
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| Sensitivity: | 0.236 nmol/min/mL |
| Applications: | Colorimetric detection, HTS |
| Application Notes: | For the measurement of enzyme activity of Lp-PLA2 (lipoprotein-associated phospholipase A2) in serum samples. |
| Species reactivity: | Human |
| Use/Stability: | Store all components, with the exception of Reagent 1, at -80°C until the kit’s expiration date. Reagent 1 may be stored at or below -20°C. Once thawed, the components can be stored at 2-8°C for up to 4 weeks. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice |
| Contents: | Lp-PLA2 assay buffer Lp-PLA2 assay substrate 5 calibrator standards QC low control QC high control |
| Scientific Background: | Approximately two-thirds of heart attacks and strokes are caused by the rupture of an unstable, rupture-prone atherosclerotic plaque. Unstable plaques are characterized by high levels of inflammatory cells and inflammatory mediators. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is produced by inflammatory cells and circulates primarily bound to low-density lipoprotein (LDL) and is to a lesser extent associated with high-density lipoprotein (HDL) in human plasma. LDL oxidation is an early key event in the pathogenesis of atherosclerosis. Elevated Lp-PLA2 levels have been found in atherosclerotic plaques and rupture lesions. |
| Technical Info/Product Notes: | The PLAQPRO™ Lp-PLA2 Assay is a colorimetric readout enzyme activity assay. During the test, Lp-PLA2 in serum samples hydrolyze the SN2 position of the substrate, 1-myristoyl-2-(4-nitrophenylsuccinyl)phosphatidylcholine. The resulting colored reaction product, 4-nitrophenol, is measured spectrophotometrically and the rate of formation of 4-nitrophenol is determined over successive measurements. The assay kit includes five Lp-PLA2 calibrator standards for use in generating a standard curve fit of change in absorbance versus Lp-PLA2 activity level in nmol/min/mL. The activity of Lp-PLA2 in serum samples is interpolated from the calibration curve. |
| UniProt ID: | Q13093 |
| Regulatory Status: | RUO - Research Use Only |
CRP (human) ELISA kit |
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PGE2 ELISA kit |
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| Highly sensitive PGE2 ELISA kit for inflammation and eicosanoid research. | ||||||
| ELISA, Colorimetric detection | Print as PDF | ||||||
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PGE2 high sensitivity ELISA kit |
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PGE2 CLIA kit |
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| Chemiluminescence | Print as PDF | ||||||
| ADI-910-001 | 96 wells | 525.00 USD | |
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PGE2 FPIA kit |
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| Fluorescence microscopy | Print as PDF | ||||||
| ADI-920-001 | 100 tests | 344.00 USD | |
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COX-2 (human), ELISA kit |
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| Most sensitive COX-II immunoassay kit commercially available for inflammation research. | ||||||
| ELISA, Colorimetric detection | Print as PDF | ||||||
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