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Big Endothelin-1 ELISA kit

Sensitive Big ET-1 ELISA kit enabling detection of Big-ET in serum and plasma in just 4.5 hours.
Do you need bulk/larger quantities?
 
For sale in Japan only.
The Big Endothelin-1 ELISA kit is a colorimetric immunometric enzyme immunoassay kit with results in 4.5 hours.

Product Specification

Alternative Name:Big ET-1
 
Sensitivity:0.02 pmol/l (0-3 pmol/l)
 
Assay Time:4.5 hours
 
Applications:ELISA, Colorimetric detection
 
Application Notes:For the quantitative determination of human Big ET-1 in serum and plasma.
 
Species reactivity:Human
 
Use/Stability:All reagents of the kit are stable at 4°C (2-8°C) until the expiry date.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:Endothelins (ET) are isopeptides produced by vascular endothelium that have potent vasoconstrictive activity. The peptides are encoded by three separate genes and processed to yield 39-residue "Big ET" molecules which are further processed to the 21 amino acid sequences designated ET-1, ET-2 and ET-3. ET action is mediated via binding to two receptors, ETA and ETB. Activation of ETA increases vasoconstriction and sodium retention, thereby increasing blood pressure. Activation of ETB receptors triggers the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells and increases urine production and elimination, thereby lowering blood pressure.
 
UniProt ID:P05305
 

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For Research Use Only. Not for use in diagnostic procedures.
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