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Regorafenib

Multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1
 
ENZ-CHM201-0001 1 mg 51.00 USD
 
ENZ-CHM201-0005 5 mg 128.00 USD
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Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC50 values of 13, 4.2, 46, 22, 7, 1.5 and 2.5 nM, respectively.

Product Specification

Alternative Name:BAY 73-4506, Fluoro-Sorafenib, 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide
 
Formula:C21H15ClF4N4O3
 
MW:482.8
 
CAS:755037-03-7
 
Purity:≥99% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:White powder.
 
Solubility:Soluble in DMSO (97mg/ml) or ethanol (1mg/ml)
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM201 structure
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ENZ-CHM201 structure

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