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TG101348

JAK2 inhibitor
 
ENZ-CHM199-0005 5 mg 90.00 USD
 
ENZ-CHM199-0010 10 mg 148.00 USD
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TG101348 inhibits JAK2(V617F) with an IC50 of 3 nM. It inhibits erythroid colony formation and also inhibits JAK2-driven STAT5 phosphorylation, cell proliferation and cell survival in JAK2 V617F cells.

Product Specification

Alternative Name:Baricitinib phosphate, LY 3009104, SAR302503, N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide
 
Formula:C27H36N6O3S
 
MW:524.7
 
CAS:936091-26-8
 
Purity:≥95% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:Beige powder.
 
Solubility:Soluble in DMSO (105mg/ml) or ethanol (21mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM199 structure
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ENZ-CHM199 structure

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