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Canertinib

EFGR inhibitor
 
ENZ-CHM196-0005 5 mg 66.00 USD
 
ENZ-CHM196-0010 10 mg 97.00 USD
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Canertinib is an orally bio-available EGFR inhibitor with potential anti-neoplastic and radio-sensitizing activities. It has IC50 values of 1.5 nM and 9.0 nM against EGFR and ErbB2 respectively, with no activity against PDGFR, FGFR, InsR, PKC, or CDK1/2/4.

Product Specification

Alternative Name:PD-183805, CI-1033, N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide
 
Formula:C24H25ClFN5O3
 
MW:485.9
 
CAS:267243-28-7
 
Purity:≥99% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:Yellow powder.
 
Solubility:Soluble in DMSO (2mg/ml) or ethanol (<9mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM196 structure
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ENZ-CHM196 structure

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EGFR
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