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AZD8055

Inhibitor of mTOR kinase selective against PI3K
 
ENZ-CHM193-0005 5 mg 66.00 USD
 
ENZ-CHM193-0010 10 mg 100.00 USD
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AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase activity with an IC50 of 0.8 nM. It shows excellent selectivity (~1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family.

Product Specification

Alternative Name:CCG-168, (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol
 
Formula:C25H31N5O4
 
MW:465.5
 
CAS:1009298-09-2
 
Purity:≥98% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:Yellow powder.
 
Solubility:Soluble in DMSO (93mg/ml) or ethanol (3mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM193 structure
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ENZ-CHM193 structure

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mTOR
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mTOR Inhibitor
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