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AZD7762 HCl

Inhibitor of checkpoint kinases
 
ENZ-CHM185-0005 5 mg 87.00 USD
 
ENZ-CHM185-0010 10 mg 117.00 USD
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Specific inhibitor for the Chk1/2 kinases with implications for possible treatment of many cancers.

Product Specification

Alternative Name:3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide hydrochloride
 
Formula:C17H19FN4O2S . HCl
 
MW:398.9
 
CAS:1246094-78-9
 
Purity:≥98% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:White powder.
 
Solubility:Soluble in DMSO (73mg/ml) or ethanol (3mg/ml)
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:Checkpoint kinases Chk1 and Chk2 are activated in response to DNA damage that results in cell cycle arrest, allowing sufficient time for DNA repair. Agents that lead to abrogation of such checkpoints have potential to increase the efficacy of such compounds as chemo- and radiotherapies.
 
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ENZ-CHM185 structure

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