Cabozantinib is a very potent inhibitor, with an IC50 of less than 10 nM for VEGFR2, MET, Kit and FLT3-ITD.
Product Details
| Alternative Name: | XL184, BMS-907351, N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
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| Formula: | C28H24FN3O5 |
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| MW: | 501.5 |
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| CAS: | 849217-68-1 |
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| Purity: | ≥99% (HPLC) |
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| Identity: | Determined by NMR. |
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| Appearance: | Off-white to white powder. |
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| Solubility: | Soluble in DMSO (100mg/ml) or ethanol (1mg/ml). |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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