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Brivanib alaninate

Inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, FGFR-1, FGFR-2, and FGFR-3
 
ENZ-CHM181-0005 5 mg 138.00 USD
 
ENZ-CHM181-0010 10 mg 224.00 USD
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Brivanib inhibits VEGFR -2 with an IC50 of 25 nmol/l and a Ki of 26 nmol/l, VEGFR-1 with an IC50 of 380 nmol/l and VEGFR-3 with an IC50 of 10 nmol/l. It also shows selectivity for FGFR-1 with an IC50 of 148 nmol/l, FGFR-2 with an IC50 of 25nmol/l and FGFR-3 with an IC50 of 68 nmol/l.

Product Specification

Formula:C22H24FN5O4
 
MW:441.5
 
CAS:649735-63-7
 
Purity:≥97% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:Yellow powder.
 
Solubility:Soluble in DMSO (74mg/ml) or ethanol (3mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM181 structure
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ENZ-CHM181 structure

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For Research Use Only. Not for use in diagnostic procedures.
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