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Axitinib

Selective inhibitor of VEGFR-1, VEGFR-2, VEGFR-3
 
ENZ-CHM169-0005 5 mg 51.00 USD
 
ENZ-CHM169-0010 10 mg 82.00 USD
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Axitinib is an oral, potent, and selective inhibitor of vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3. Axitinib is marketed under the name Inlyta®, and if one previous systemic therapy for kidney cell cancer has failed, axitinib is indicated. The IC50 numbers reported for Axitinib are sub to low nanomolar in range.

Product Specification

Alternative Name:AG-013736
 
Formula:C22H18N4OS
 
MW:386.5
 
CAS:319460-85-0
 
Purity:≥95% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:Beige powder.
 
Solubility:Soluble in DMSO (42mg/ml) or ethanol (1mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM169 structure
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ENZ-CHM169 structure

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