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BKM120

Potent inhibitor of PI3Kα
 
ENZ-CHM167-0005 5 mg 87.00 USD
 
ENZ-CHM167-0010 10 mg 148.00 USD
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NVP-BKM120 is a potent, selective, orally bioavailable Class I PI3Kα Inhibitor with IC50 of 20nM, currently in phase II clinical trials for the treatment of cancer. It exhibits lower potency against class III and class IV PI3Ks.

Product Specification

Alternative Name:Buparlisib, NVP-BKM120
 
Formula:C18H21F3N6O2
 
MW:410.4
 
CAS:944396-07-0
 
Purity:≥97% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:White powder.
 
Solubility:Soluble in DMSO (44mg/ml) or ethanol (<1mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM167 structure
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ENZ-CHM167 structure

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PI3 kinase
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