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PLX4720

Potent and selective B-Raf V600E inhibitor
 
ENZ-CHM159-0005 5 mg 87.00 USD
 
ENZ-CHM159-0010 10 mg 112.00 USD
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Equally potent to c-Raf-1 (Y340D and Y341D mutations), and shows 10-fold selectivity for B-Raf V600E over wild-type B-Raf.

Product Specification

Alternative Name:N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
 
Formula:C17H14ClF2N3O3S
 
MW:413.8
 
CAS:918505-84-7
 
Purity:≥99% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:Beige powder.
 
Solubility:Soluble in DMSO (83mg/ml) or ethanol (1mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM159 structure
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ENZ-CHM159 structure

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