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Tofacitinib

Inhibitor of JAK3
 
ENZ-CHM155-0005 5 mg 84.00 USD
 
ENZ-CHM155-0010 10 mg 128.00 USD
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Tofacitinib is an inhibitor of JAK3 with an IC50 of 1 nM. It shows up to 100-fold less potency against JAK2 and JAK1.

Product Specification

Alternative Name:Tasocitinib, 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
 
Formula:C16H20N6O
 
MW:312.4
 
CAS:477600-75-2
 
Purity:≥98% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:Pale powder.
 
Solubility:Soluble in DMSO (63mg/ml), ethanol (1mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
ENZ-CHM155 structure
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ENZ-CHM155 structure

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