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Simvastatin . sodium salt

Competitive inhibitor of HMG-CoA reductase. Suppresses TNF-induced NF-κB activation.
 
ENZ-CHM142-0005 5 mg 117.00 USD
 
ENZ-CHM142-0010 10 mg 214.00 USD
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Simvastatin is marketed under the trade name Zocor™ and is often prescribed in combination with ezetimibe (Zetia) to treat dyslipidemia. This drug combination is known commercially as Vytorin or Inegy. Simvastatin also suppresses TNF-induced NF-κB activation, which potentiates apoptosis in human myeloid leukemia cells and thus, may be useful in treating cancer.

Product Specification

Alternative Name:(βR,​δR,​1S,​2S,​6R,​8S,​8aR)-​8-​(2,​2-​dimethyl-​1-​oxobutoxy)-​1,​2,​6,​7,​8,​8a-​hexahydro-​β,​δ-​dihydroxy-​2,​6-​dimethyl-​1-​naphthaleneheptanoic acid .​ monosodium salt
 
Formula:C25H39O6 . Na
 
MW:458.6
 
CAS:101314-97-0
 
Purity:≥97% (HPLC)
 
Appearance:White powder solid.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-80°C
 
ENZ-CHM142 structure
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ENZ-CHM142 structure

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HMG-CoA reductase
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