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mTOR inhibitor WYE-132

Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.
 
ENZ-CHM140-0001 1 mg 82.00 USD
 
ENZ-CHM140-0005 5 mg 265.00 USD
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A highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Shows an anti-proliferative activity against a variety of tumor cell lines. WYE-132 causes inhibition of protein synthesis and cell size, induction of apoptosis, and cell cycle progression.

Product Specification

Alternative Name: 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132
 
Formula:C27H33N7O4
 
MW:519.6
 
CAS:1144068-46-1
 
Purity:≥99% (HPLC)
 
Appearance:White powder solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-80°C
 
ENZ-CHM140 structure
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ENZ-CHM140 structure

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For Research Use Only. Not for use in diagnostic procedures.
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