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mTOR inhibitor WYE-28

Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
 
ENZ-CHM137-0001 1 mg 92.00 USD
 
ENZ-CHM137-0005 5 mg 301.00 USD
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Cell-permeable. A potent, selective, and ATP-competitive mTOR (mammalian target of rapamycin) inhibitor (IC50 = 0.08 nM). WYE-28 displays 75-fold selectivity over PI3Kα (IC50 = 6 nM).

Product Specification

Alternative Name:4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester
 
Formula:C30H34N8O5
 
MW:586.6
 
CAS:1062172-60-4
 
Purity:≥97% (HPLC)
 
Appearance:White powder solid.
 
Solubility:Soluble in DMSO.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-80°C
 
ENZ-CHM137 structure
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ENZ-CHM137 structure

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