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MyoD1 Recombinant monoclonal antibody (rMYD712)

 
ENZ-ABS792-0100 100 µg 595.00 USD
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Product Specification

Alternative Name:Myoblast determination protein 1, Myogenic factor 3
 
Clone:rMYD712
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant human MyoD1.
 
UniProt ID:P15172
 
Species reactivity:Human
 
Specificity:Recognizes a phospho-protein of 45kDa, identified as MyoD1.
 
Crossreactivity:Does not cross react with myogenin, Myf5, or Myf6.
 
Applications:IHC
 
Application Notes:Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In 1X PBS containing 0.1 mg/ml BSA and 0.05% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing's sarcomas and alveolar soft part sarcomas.
 
MyoD1 Recombinant monoclonal antibody (rMYD712) IHC
FFPE human Rhabdomyosarcoma stained with PAX7 antibody.
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MyoD1 Recombinant monoclonal antibody (rMYD712) IHC

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