Alternative Name: | Pairex box protein Pax-7, HuP1 |
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Clone: | PBPX7 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Recombinant PAX7 fragment (aa 300-600). |
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UniProt ID: | P23759 |
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Species reactivity: | Human
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Applications: | IHC, WB
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Purity Detail: | Protein G affinity purified. |
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Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA and 0.05% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2). |
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Regulatory Status: | RUO - Research Use Only |
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