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Syntaxin 6 monoclonal antibody (3D10)

 
ENZ-ABS750-0200 200 µg 628.00 USD
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Product Details

Alternative Name:STX6
 
Clone:3D10
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant rat Syntaxin 6.
 
UniProt ID:Q63635
 
Source:Purified from hybridoma tissue culture supernatant.
 
Species reactivity:Human, Mouse, Rat
Hamster
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~35kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles.
 
Regulatory Status:RUO - Research Use Only
 
Syntaxin 6 monoclonal antibody (3D10) SDS-PAGE
SDS-PAGE analysis of ENZ-ABS750: Lane 1: MW Marker, Lane 2 and Lane 3: Syntaxin 6 monoclonal antibody (3D10), resolved under reduced and non-reduced condition.
Syntaxin 6 monoclonal antibody (3D10) WB
Western Blot analysis of ENZ-ABS750: Lane 1: MW Marker, Lane 2: CHO-K1 lysate, Lane 3: mouse brain lysate, Lane 4: rat brain lysate.
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Syntaxin 6 monoclonal antibody (3D10) SDS-PAGE Syntaxin 6 monoclonal antibody (3D10) WB

Product Literature References

Subcellular localization of hippocampal ryanodine receptor 2 and its role in neuronal excitability and memory: F. Hiess, et al.; Commun. Biol. 5, 183 (2022), Abstract;

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