Product Details
Alternative Name: | STX6 |
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Clone: | 3D10 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Recombinant rat Syntaxin 6. |
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UniProt ID: | Q63635 |
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Source: | Purified from hybridoma tissue culture supernatant. |
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Species reactivity: | Human, Mouse, Rat Hamster
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Applications: | IP, WB
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Recommended Dilutions/Conditions: | Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~35kDa by Western blot. |
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Purity Detail: | Protein G affinity purified. |
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Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles. |
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Regulatory Status: | RUO - Research Use Only |
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SDS-PAGE analysis of ENZ-ABS750: Lane 1: MW Marker, Lane 2 and Lane 3: Syntaxin 6 monoclonal antibody (3D10), resolved under reduced and non-reduced condition.
Western Blot analysis of ENZ-ABS750: Lane 1: MW Marker, Lane 2: CHO-K1 lysate, Lane 3: mouse brain lysate, Lane 4: rat brain lysate.
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Product Literature References
Subcellular localization of hippocampal ryanodine receptor 2 and its role in neuronal excitability and memory: F. Hiess, et al.; Commun. Biol.
5, 183 (2022),
Abstract;
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