Alternative Name: | Triggering receptor expressed on myeloid cells 2 isoform 1, Triggering receptor expressed on monocytes 2 |
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Clone: | 2B5 |
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Host: | Mouse |
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Isotype: | IgG3κ |
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Immunogen: | Recombinant human TREM2 (aa 19-161) purified from E. coli. |
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UniProt ID: | Q9NZC2 |
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Source: | Purified from ascites. |
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Species reactivity: | Human
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Applications: | ELISA, Flow Cytometry, ICC, IF, WB
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Recommended Dilutions/Conditions: | Western Blot (1:1,000). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein G affinity purified |
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Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. |
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Regulatory Status: | RUO - Research Use Only |
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