| Alternative Name: | toll-like receptor 7 |
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| Clone: | 4F4 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Recombinant human TLR7 (aa 451-500) purified from E. coli. |
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| UniProt ID: | Q9NYK1 |
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| Source: | Purified from ascites. |
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| Species reactivity: | Human
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| Applications: | ELISA, Flow Cytometry, ICC, IF
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| Purity Detail: | Protein G affinity purified |
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| Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. |
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| Regulatory Status: | RUO - Research Use Only |
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