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PD-1 monoclonal antibody (4F12)

 
ENZ-ABS737-0100 100 µl 355.00 USD
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Product Specification

Alternative Name:Programmed cell death 1, CD279
 
Clone:4F12
 
Host:Mouse
 
Isotype:IgG2bκ
 
Immunogen:Recombinant human PDCD1 (aa 21-167) purified from E. coli.
 
UniProt ID:Q15116
 
Source:Purified from ascites.
 
Species reactivity:Human
 
Applications:ELISA, Flow Cytometry, ICC, IF, WB
 
Recommended Dilutions/Conditions:Western Blot (1:500).
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified
 
Formulation:Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney.
 

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