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NKp46/NCR1 monoclonal antibody (N1D9)

 
ENZ-ABS736-0100 100 µl 390.00 USD
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Product Specification

Alternative Name:Natural cytotoxicity triggering receptor 1 isoform a, NCR1, CD335
 
Clone:n1D9
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant human Nkp46/NCR1 (aa 22-255) purified from E. coli.
 
UniProt ID:O76036
 
Source:Purified from hybridoma tissue culture supernatant.
 
Species reactivity:Human
 
Applications:ELISA, Flow Cytometry
 
Formulation:Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
 

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