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NKp46/NCR1 monoclonal antibody (N1D9)

 
ENZ-ABS735-0100 100 µl 355.00 USD
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Product Specification

Alternative Name:Natural cytotoxicity triggering receptor 1 isoform a, NCR1, CD335
 
Clone:n1D9
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant human Nkp46 (aa 22-255) purified from E. coli.
 
UniProt ID:O76036
 
Source:Purified from ascites.
 
Species reactivity:Human
 
Applications:ELISA, Flow Cytometry
 
Purity Detail:Protein G affinity purified
 
Formulation:Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
 
NKp46/NCR1 monoclonal antibody (N1D9) FC PBMC
Flow cytometry analysis of NKp46/NCR1 in PBMC. The cell was stained at 2-5 µg for 1x106 cells (red). A Goat anti mouse IgG (Alexa fluor 488) was used as the secondary antibody. Mouse monoclonal IgG was used as the isotype control (darkgray), cells without incubation with primary and secondary antibody was used as the negative control (light gray).
NKp46/NCR1 monoclonal antibody (N1D9) FC HeLa
Flow cytometry analysis of NKp46/NCR1 in HeLa cells. The cell was stained at 2-5 µg for 1x106 cells (red). A Goat anti mouse IgG (Alexa Fluor 488) was used as the secondary antibody. Mouse monoclonal IgG was used as the isotype control (dark gray), cells without incubation with primary and secondary antibody was used as the negative control (light gray).
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NKp46/NCR1 monoclonal antibody (N1D9) FC PBMC NKp46/NCR1 monoclonal antibody (N1D9) FC HeLa

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