Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

LIGHT monoclonal antibody (7B9E12)

 
ENZ-ABS699-0100 100 µg 457.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:TNFSF14, CD258, HVEML
 
Clone:7B9E12
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Extracellular domain of human LIGHT.
 
UniProt ID:O43557
 
Species reactivity:Human
 
Applications:Flow Cytometry, ICC, IF, IHC (PS), WB
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:LIGHT, also known as Tumor Necrosis Factor Superfamily member 14 (TNFSF14), is a co-stimulatory molecule that can regulate T-cell activation and has recently been identified as an immune checkpoint protein. LIGHT binds to two different receptors, Herpes Virus Entry Mediator (HVEM) and Lymphotoxin beta Receptor (LTβR). While LIGHT binding to HVEM delivers a co-stimulatory signal to T cells, LIGHT binding to LTβR is critical for the formation of lymphoid structures which can stimulate T cell infiltration and activation of a tumor microenvironment, leading to rapid T cell-mediated tissue destruction. LIGHT may become a potent tool in anti-cancer treatment.
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
LIGHT
By biological activity:
LIGHT Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,