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CTLA4 monoclonal antibody (1E6)

 
ENZ-ABS696-0100 100 µg 457.00 USD
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Product Specification

Alternative Name:Cytotoxic T-lymphocyte associated protein 4, CD152
 
Clone:1E6
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Extracellular domain of human CTLA-4.
 
UniProt ID:P16410
 
Species reactivity:Human
 
Applications:ICC, IF, IHC (PS), WB
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), also known as CD152, is a member of the immunoglobulin superfamily that is expressed by activated T cells and transmits an inhibitory signal to T cells. CTLA-4 also functions as an immune checkpoint protein, and anti- CTLA-4 antibodies have been successfully used in the treatment of cancer. Mutations in the CTLA-4 gene have been implicated in multiple autoimmune diseases.
 

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