Alternative Name: | ESR |
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Clone: | C-542 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human Estrogen Receptor α. |
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UniProt ID: | P03372 |
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GenBank ID: | M12674 |
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Source: | Purified from hybridoma tissue culture supernatant. |
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Species reactivity: | Human, Mouse, Rat Hamster
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Applications: | ICC, IHC, IP, WB
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Recommended Dilutions/Conditions: | Western Blot (1:500, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of 66.3 kDa by Western blot. |
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Purity Detail: | Protein G affinity purified. |
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Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | The Estrogen receptors (ER), mainly ERalpha and ERbeta, are members of the nuclear steroid hormone receptor family and are composed of three domains, an N-terminal domain required for maximal transactivation function (TAF), a DNA binding domain, and a steroid binding domain. Estrogen has pleiotropic effects on the growth, development, and maintenance of diverse tissues. |
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Regulatory Status: | RUO - Research Use Only |
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