| Alternative Name: | MKI67 |
| |
| Host: | Mouse |
| |
| Isotype: | IgG |
| |
| Immunogen: | Recombinant Ki-67 |
| |
| UniProt ID: | P46013 |
| |
| Species reactivity: | Human
|
| |
| Applications: | IHC
|
| |
| Recommended Dilutions/Conditions: | Immunohistochemistry (RTU)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
| |
| Purity Detail: | Affinity purified. |
| |
| Formulation: | Liquid. Ready-to-use solution in PBS containing stabilizers and preservatives. |
| |
| Use/Stability: | When stored correctly, the antibody is stable until the date indicated on the label. To ensure proper stability of the antibody after each run, replace the cap and immediately place the bottle in a refrigerator in an upright position. |
| |
| Handling: | Avoid freeze/thaw cycles. |
| |
| Shipping: | Blue Ice |
| |
| Short Term Storage: | +4°C |
| |
| Long Term Storage: | +4°C |
| |
| Scientific Background: | Ki-67 is a nuclear, non-histone protein that is expressed only during active phases of the cell cycle (G1, S, G2 and M), but not in the resting phases (G0 and G1 early phase). Although the antigen has also been associated with ribosomal RNA transcription, it is strongly linked to cell proliferation and has thus been indicated as an effective marker in grading the proliferation rate of tumors, including those of the brain, breast, cervix, and prostate. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
