Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

LAG-3 (human) recombinant monoclonal antibody (L4-PL33)

 
ENZ-ABS677-0100 100 µg 407.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:Lymphocyte activation gene-3, FDC protein, CD223
 
Clone:L4-PL33
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Synthetic peptide corresponding to 30 aa (GPPAAAPGHPLAPGPHPAAPSSWGPRPRRY) from the first N-terminal D1 domain of human LAG-3 (lymphocyte activation gene-3).
 
UniProt ID:P18627
 
Species reactivity:Human
 
Specificity:Recognizes the 30 aa extra-loop of the first N-terminal D1 domain of LAG-3.
 
Applications:ELISA, Flow Cytometry, ICC, IHC (FS), IP, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (frozen sections, 1:150)
Western Blot (5 µg/ml)
Immunoprecipitation (10 µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Purified.
 
Formulation:Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
 
Use/Stability:Stable for at least 6 months after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.
 

Related Products

LAG-3 (human) monoclonal antibody (17B4) (biotin conjugate) 

ELISA, WB | Print as PDF
 
ALX-804-806B-C100 100 µg Biotin 496.00 USD
Do you need bulk/larger quantities?
 

LAG-3 (human) monoclonal antibody (17B4) (FITC conjugate) 

Flow Cytometry | Print as PDF
 
ALX-804-806F-C100 100 µg FITC 496.00 USD
Do you need bulk/larger quantities?
 

LAG-3 (human) monoclonal antibody (17B4) (ATTO 488 conjugate) 

Flow Cytometry, ICC | Print as PDF
 
ALX-804-806TD-T100 100 tests ATTO 488 516.00 USD
Do you need bulk/larger quantities?
 

LAG-3 (human) monoclonal antibody (17B4) (ATTO 647N conjugate) 

Flow Cytometry, ICC | Print as PDF
 
ALX-804-806TS-T100 100 tests ATTO 647N 403.00 USD
Do you need bulk/larger quantities?
 

LAG-3 (human):Fc (human), (recombinant) 

Produced in CHO cells. The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1., ≥99% (SDS-PAGE), ELISA, Flow Cytometry | Print as PDF
 
ALX-522-078-C050 50 µg 508.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
LAG
By biological activity:
LAG Recombinant antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2018 Enzo Life Sciences, Inc.,