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IL-6 receptor Recombinant monoclonal antibody (rhPM-1) (Rabbit IgGκ)

 
ENZ-ABS550-0200 200 µg 440.00 USD
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Product Specification

Alternative Name:Interleukin-6 receptor, IL6R, MRA
 
Clone:rhPM-1 (Tocilizumab)
 
Host:Rabbit
 
Isotype:IgGκ
 
Immunogen:This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
 
UniProt ID:A0N0L5
 
Species reactivity:Human
 
Specificity:Recognizes both the membrane bound and soluble forms of human IL-6R.
 
Applications:ELISA
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% Proclin 300.
 
Use/Stability:Stable at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
 
Technical Info/Product Notes:This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
 

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