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IL-2Rα (CD25) Recombinant monoclonal antibody (Rabbit IgGκ)

 
ENZ-ABS546-0200 200 µg 440.00 USD
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Product Specification

Alternative Name:Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2R subunit alpha, IL-2-RA, TAC antigen, p55
 
Clone:Basiliximab
 
Host:Rabbit
 
Isotype:IgGκ
 
Immunogen:Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
 
UniProt ID:P01589
 
Species reactivity:Human
 
Specificity:Recognizes human IL-2R and binds to the epitope E116RIYHFV122 within the extracellular domain of the CD25 subunit. Binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R (αβγc) – T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
 
Applications:Flow Cytometry, IF, IHC, WB, FUNC
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% Proclin 300.
 
Use/Stability:Stable at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
 

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