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erbB-2 Recombinant monoclonal antibody (4D5-8) (Rabbit IgGκ)

 
ENZ-ABS489-0200 200 µg 440.00 USD
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Product Specification

Alternative Name:Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Tyrosine kinase-type cell surface receptor HER2, CD340
 
Clone:4D5-8 (Trastuzumab)
 
Host:Rabbit
 
Isotype:IgGκ
 
Immunogen:A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
 
UniProt ID:P04626
 
Species reactivity:Human
 
Applications:ELISA, Flow Cytometry, IHC
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% Proclin 300.
 
Use/Stability:Stable at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
 
Technical Info/Product Notes:This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
 

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