Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Globo H (human) monoclonal antibody (VK9)

 
ENZ-ABS379-0050 50 µg 299.00 USD
 

Product Specification

Clone:VK9
 
Host:Mouse
 
Isotype:IgG3κ
 
Immunogen:Globo H-KLH (keyhole limpet hemocyanin) synthetic conjugate
 
Species reactivity:Human
 
Applications:Flow Cytometry, IHC (PS), WB, Fluorescence microscopy
 
Recommended Dilutions/Conditions:Western Blot (5 µg/mL)
Immunohistochemistry (paraffin sections, 5 µg/mL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Affinity chromatography purified.
 
Formulation:Liquid. 0.2 µM filtered solution in PBS, pH 7.2, containing 0.09% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Globo H is a hexasaccharide formed from the pentasaccharide precursor, SSEA3 (stage-specific embryonic antigen 3). It is a member of a family of antigenic carbohydrates expressed on the surface of cancer cells as glycolipids and possibly glycoproteins. Globo H is overexpressed on many carcinomas, such as breast, colon, ovarian, gastric, pancreatic, lung, and prostate. Expression of Globo H in carcinomas include more than half of all ductal, lobular, and tubular breast carcinomas, but not in non-epithelial breast tumors. Cancer stem cells and human embryonic stem cells also express global H, although expression decreases when cells are differentiated toward both neural progenitor cells and to a lesser extent in endodermal lineage cells. Expression in normal tissues is limited to cells composing secretory borders. Globo H is considered a target for immunotherapy of many epithelial cancers.
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
globo H
By biological activity:
globo H Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,