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FOLR1 (human) monoclonal antibody (548908)

 
ENZ-ABS378-0100 100 µg 415.00 USD
 

Product Specification

Alternative Name:Folate-binding protein, gp38, FRα, Folate Receptor α, Folate Receptor 1
 
Clone:548908
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Chinese hamster ovary cell line CHO derived recombinant human FOLR1 Arg25Met233.
 
UniProt ID:P15328
 
Species reactivity:Human
 
Crossreactivity:Does not cross-react with recombinant human FOLR2, 3 or 4 in direct ELISAs.
 
Applications:ELISA, Flow Cytometry, ICC, WB
 
Recommended Dilutions/Conditions:ELISA (0.1-0.4 µg/ml (Detection), 2-8 µg/mL (Capture))
Flow Cytometry (2.5 µg/106 cells)
Immunocytochemistry (8-25 µg/mL)
Western Blot (2 µg/mL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A/G purified from hybridoma culture supernatant.
 
Formulation:Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.
 
Reconstitution:Reconstitute at 0.5 mg/mL in sterile PBS.
 
Use/Stability:Stable one month reconstituted under sterile conditions at 4°C.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:-20°C
 
Long Term Storage:-20°C
 
Scientific Background:The protein encoded by this gene is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid, several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Human FOLR1 shares 83% amino acid sequence identitiy with mouse and rat FOLR1. FOLR1 is up-regulated on many carcinomas, such as ovarian, and predominantly expressed on epithelial cells.
 
Technical Info/Product Notes:37 - 42 kDa protein
 

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