Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

RbAp46 polyclonal antibody (biotin conjugate)

 
ENZ-ABS285-0100 100 µg 275.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:Histone-binding protein RBBP7, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, Histone acetyltransferase type B subunit
 
Host:Rabbit
 
Isotype:IgG
 
Immunogen:Synthetic peptide corresponding to aa 1-13 (MASKEMFEDTVEEC) of human RbAp46.
 
UniProt ID:Q16576
 
Species reactivity:Human
 
Specificity:Recognizes human RbAp46.
 
Applications:ICC, IF, IHC, WB
 
Application Notes:Detects a band of ~46kDa by Western blot.
 
Purity Detail:Antigen affinity chromatography
 
Formulation:Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:RbAp46 is a nuclear protein that has been shown to interact directly with retinoblastoma protein and is a component of the mSin3 corepressor complex as are the histone deacetylase proteins (HDACs). RbAp46 shares about 75% sequence identity with the closely related RbAp48, and appears to be functionally related to the yeast MSI1 protein in that overexpression of RbAp46 suppresses heat shock sensitivity in a RAS pathway dependent manner. RbAp46 has also been demonstrated to be up-regulated by the Wilms’ tumor suppressor gene product, WT1. Additionally, cells transfected with RbAp46 have shown strong inhibition of growth.
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
RbAp
By biological activity:
RbAp Polyclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Epigenetics
Epigenetics
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,