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Chromogranin A polyclonal antibody

ENZ-ABS268-0100 100 µl 343.00 USD
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Product Specification

Alternative Name:CgA, CHGA, Parathyroid secretory protein 1
Immunogen:Synthetic peptide corresponding to aa 1-15 (L1PVNSPMNKGDTEVM15) of native human chromogranin A, conjugated to KLH.
UniProt ID:P10645
Species reactivity:Human
Crossreactivity:Expected reactivity due to sequence homology with bovine, chimpanzee, dog, horse, pig, mouse, rat.
Applications:ELISA, IHC
Formulation:Liquid. In PBS containing 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Chromogranin A (CgA) is a prohormone which is proteolytically processed in neurons prior to axonal transport. The differential expression of chromogranin A fragments in neuronal populations suggests distinct functional roles for each CgA-derived peptide. Immunohistochemical localization of CgA has been used as a marker for the identification and prognostic assessment of neuroendocrine tumours and CgA has also been reported to be a component of senile plaques in the brains of demented individuals.

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